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As an animal walks, runs, jumps and plays, tremendous stress is placed on all components of the joints. Years of wear and tear due to normal aging, disease, injury or genetic conditions break down cartilage, leading to instability. Eventually cartilage cells cannot synthesize enough proteoglycans to help cartilage heal and signs of discomfort may appear. Later, inflammatory chemicals further disrupt cellular function and may eventually damage the bone. Nutri-Vet produces a variety of joint and pain relief products formulated by veterinarians to support joint function and motility and reduce stress, strain and shock to joints. When to use: Elderly animals Non-specific lameness Difficulty rising Stiff and sore after exercise Giant breeds Active adults Working dogs